Tesofensine is a triple reuptake inhibitor that affects dopamine, norepinephrine, and serotonin—three key neurotransmitters that play a role in appetite control and energy regulation. Initially studied for neurodegenerative disorders like Parkinson’s and Alzheimer’s disease, it was found to significantly reduce body weight in clinical trials.
Tesos 0.5mg is now used as a cutting-edge solution for those struggling with appetite control, food cravings, and stubborn fat loss. It helps users eat less without feeling deprived and can be used in conjunction with exercise and a calorie-controlled diet for optimal fat loss results. It is suitable for both men and women and often used in advanced weight management protocols.
Benefits
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Powerful appetite suppression
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Reduces cravings and snacking urges
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Supports consistent weight and fat loss
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Slight metabolic stimulation
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Improves diet adherence and compliance
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Once-daily dosing with long-lasting effects
Side effects
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Mild increase in heart rate or blood pressure
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Insomnia or restlessness (especially if taken late)
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Dry mouth
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Mild nausea or dizziness (usually transient)
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Headaches or mood changes in sensitive individuals
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Should not be combined with SSRIs or MAO inhibitors (risk of serotonin syndrome)
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Not recommended for individuals with cardiovascular disease, anxiety disorders, or uncontrolled hypertension
Dosages & Protocol
Dosages for Men and Women:
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Beginner dose: 0.25mg daily for the first 5–7 days to assess tolerance
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Standard dose: 0.5mg once daily in the morning
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Maximum dose (if well-tolerated): 0.75mg daily under guidance
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Duration: Can be used continuously or cycled 8–12 weeks with breaks
Should be taken early in the day to avoid interference with sleep.
How to administer
Take orally with water, preferably in the morning on an empty stomach or with a light meal. Avoid taking in the evening to prevent sleep disruption.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Do not expose to high heat or humidity.
Half life & detectability
Half-Life: Approximately 24–36 hours, allowing for once-daily dosing
Detection Time: Not typically screened for in standard drug tests, but may be detectable in specialized panels for up to several days
For athletes subject to drug testing, it is crucial to consider these detection times to avoid positive tests for banned substances.
