PT-141 (Bremelanotide) is a synthetic peptide originally derived from Melanotan II. Unlike traditional ED medications (like Viagra or Cialis), which act on the vascular system, PT-141 works directly on the central nervous system, specifically targeting the hypothalamus to boost sexual desire and stimulation. This makes it effective even in cases where vascular performance enhancers may not work—such as in women or men with psychological or neurologically driven sexual dysfunction.
Nicknamed the “Lovers Peptide,” PT-141 is widely used to increase libido, heighten sexual satisfaction, and enhance arousal in both men and women. Effects are typically felt within an hour and can last up to 12 hours.
Benefits
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Increases sexual desire and arousal
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Enhances physical and mental sexual response
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Effective for both men and women
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Works independently of hormonal or circulatory function
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May improve sexual confidence and satisfaction
Side effects
PT-141 Lovers Peptide 10mg is generally well-tolerated, but side effects may include:
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Temporary nausea (especially with higher doses)
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Flushing or redness in the face and chest
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Mild headache or fatigue
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Increased heart rate in some individuals
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Rarely: nasal congestion or injection site irritation
Starting with a lower dose can help minimize side effects.
Dosages & Protocol
Dosages for Men and Women:
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Starting dose: 500mcg (0.5mg)
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Typical dose: 1mg taken 30–60 minutes before sexual activity
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Max dose: Up to 2mg per use depending on tolerance
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Effects can last 6–12 hours
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Use no more than 3 times per week to prevent desensitization
PLEASE MAKE USE OF OUR PEPTIDE CALCULATOR FOR FURTHER DOSAGE GUIDANCE.
How to administer – reconstitution and injection
Reconstitution:
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Reconstitute 10mg vial with 1ml of bacteriostatic water
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Inject the water slowly along the side of the vial
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Swirl gently (do not shake) until dissolved
Injection:
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Use a 1ml insulin syringe
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Administer subcutaneously into the abdominal area or thigh
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Dosing reference (if reconstituted with 1ml):
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500mcg = 5 units
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1mg = 10 units, and so on
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Storage
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Before reconstitution: Store in a refrigerator or cool, dry place
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After reconstitution: Store at 2–8°C and use within 30 days
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Do not freeze. Protect from light and heat
Half life & detectability
Half-Life: Approximately 2.5 hours, but effects can persist for up to 12 hours
Detection Time: Not commonly tested in standard drug screenings, but may be detectable in advanced assays for several days
For athletes subject to drug testing, it is crucial to consider these detection times to avoid positive tests for banned substances.