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MGF is a splice variant of the IGF produced by a frame shift if the IGF gene and PEGylated to improve stability.

Original price was: R2620.Current price is: R2358.

SKU: CP040


MGF (Mechano Growth Factor), is a new and innovative form of the IGF produced by a frame shift if the IGF gene, namely Mechano Growth Factor, which is PEGylated to improve stability that outperforms natural MGF many times over.

Mechano Growth Factor is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream.

Mechano Growth Factor is only stable in the blood stream for only a few minutes. Research has shown that MGF helps increase the muscle stem cell count, so that more may fuse and become part of adult muscle cells.

Mechano Growth Factor exhibits local effects in skeletal muscle and without cannot travel through the body without modification.

The problem with synthetic Mechano Growth Factor is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Growth Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream.

It is also short acting, so stability is not an issue. By PEGylating the Mechano Growth factor it is almost as efficient as local produced Mechano Growth Factor when used intramuscularly.

This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule.

The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein

Recently MGF has gained a lot of popularity due to its various benefits. Not only does it help in adding new muscle growth, but it also helps cure few muscle disorders. As it helps in strengthening bones too you can also use it for bone-related diseases.

MGF results are quite fascinating. It produces new muscle fibers and helps to stimulate growth in affected areas. It may also promote the retention of nitrogen in muscle fibers while increasing protein synthesis.

This peptide can be very helpful to bodybuilders as they help in creating new muscle tissues, which in turn would increase the total muscle mass of the body.

Many people come across the GHRP 2 vs GHRP 6 dilemma. What is the distinction between these two? The main difference between IGF-1 derived PEG-MGF and MGF is that the latter stimulates myoblasts through the stimulation of different receptors. Whereas PEG-MGF increases the muscle stem cell count so that many more cells fuse and become a part of adult muscles.

Additional information

Chemical Composition




Pack Size

10 Vials


Cooper Pharma

Dosage Instructions

Athletes who use it for hypertrophy (increase in the volume of an organ or tissue) and recovery tend to do so once daily. MGF dosage of 200 to 500 µg on off days while a dose of 100 to 200 µg on post works out intervals are most common. It is injected subcutaneously.


If you decided to take capsulated MGF, we recommend you start with 3 capsules per day.

As for the recommended cycle, it is commonly incorporated for a maximum of four weeks.


The most preferable way to take MGF is to inject it intramuscularly. But due to its long half-life, you can also inject it under the skin into the fat tissues (belly, buttocks, thighs). Even if you inject it under the skin, it will still make its way to the receptors present on the muscle cells and be as effective.

Effect on Cycle

Here are a few benefits of PEG-MGF:

  • Promotion Of Skeletal Muscle – Research has found that when MGF is injected directly into the muscle it helps to protect it. In doing so it decreases the expression of some specific inflammatory hormones and lowers the oxidation stress.
  • Anti-aging Benefits and Fat Metabolism – This happens when MGF stimulates the IGF-1 receptors which lead to decrease aging and an increase in lean body mass. Along with that, it poses a significant role in fat metabolism.
  • Heart Muscle Repair – MGF inhibits apoptosis that cardiac muscle cells go through after hypoxia. MGF helps in the recruitment of the cardiac stem cells to the injured site, and it may help to heal the heart after a heart attack.

Additional Information

Indeed, there are many positive effects associated with MGF peptide based on scientific research and animal testing. But it is important to keep in mind that there have been some records of unfavourable effects related to MGF.

These negative MGF side effects are


  • One of the negative effects of MGF found after animal testing is Hypoglycaemia or ‘low blood sugar’. As -MGF increases the efficiency of cellular functionality, blood sugar achieves its functional goal too quickly thus resulting in Hypoglycaemia.
  • Swelling of the extremities which mean limbs, arms, and legs (particularly hands and feet)
  • The blood pressure of the body drops, in some cases, when you take this peptide.
  • It is also associated with irregular cardiovascular activities. So much so that it can even lead to cardiac arrest in some cases.

Shipping & Returns

Looking for a bit more information about how online orders are processed? Here are some commonly asked questions and answers regarding our Online Shop!

How do I know that my order has been received?
When your order has been successfully received by our system, you’ll see a confirmation page. A confirmation e-mail will also be sent to the e-mail address you specified, giving the details of your order. This confirmation indicates that your order has been received. If you can’t find this confirmation email, check your spam or junk mail folders.

Fulfilment of your order may be impacted by stock availability however an email will be forwarded to you once your order is packed and ready for shipping. This email will include tracking details so that you can trace your parcel.

I live outside of South Africa, can I place an order?
Unfortunately, we only deliver to addresses within South Africa at this stage.

I live in South Africa, how much does shipping cost?
Shipping from our Anabolics ZA site is only R 150 nationwide!

When will be delivery arrive?
All orders are sent via a door-to-door courier service. Please make sure that there is someone to receive your order at your nominated address between Monday to Friday, 9:00am-5:00pm. Please note that your order will take 2 – 3 working days from date of payment to arrive. Deliveries to outlying areas may take longer.

Can I make a change or cancel my order after purchasing?
No changes and cancellations are not possible once the order has been processed and an order confirmation screen is displayed.

What is the return policy and process?
Anabolics ZA products are medicines so we cannot refund or accept returns. If you are unsatisfied with your order in any way, please contact us within 30 days of your order via email and we will do our best to resolve your issue.

I have an issue with my order – what do I do next?
Contact us if you have any queries about your order. Refer to your order number as a reference.

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