MGF (Mechano Growth Factor), is a new and innovative form of the IGF produced by a frame shift if the IGF gene, namely Mechano Growth Factor, which is PEGylated to improve stability that outperforms natural MGF many times over.
Mechano Growth Factor is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream.
Mechano Growth Factor is only stable in the blood stream for only a few minutes. Research has shown that MGF helps increase the muscle stem cell count, so that more may fuse and become part of adult muscle cells.
Mechano Growth Factor exhibits local effects in skeletal muscle and without cannot travel through the body without modification.
The problem with synthetic Mechano Growth Factor is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Growth Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream.
It is also short acting, so stability is not an issue. By PEGylating the Mechano Growth factor it is almost as efficient as local produced Mechano Growth Factor when used intramuscularly.
This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule.
The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein
Recently MGF has gained a lot of popularity due to its various benefits. Not only does it help in adding new muscle growth, but it also helps cure few muscle disorders. As it helps in strengthening bones too you can also use it for bone-related diseases.
MGF results are quite fascinating. It produces new muscle fibers and helps to stimulate growth in affected areas. It may also promote the retention of nitrogen in muscle fibers while increasing protein synthesis.
This peptide can be very helpful to bodybuilders as they help in creating new muscle tissues, which in turn would increase the total muscle mass of the body.
THE DIFFERENCE BETWEEN MGF AND PEG-MGF:
Many people come across the GHRP 2 vs GHRP 6 dilemma. What is the distinction between these two? The main difference between IGF-1 derived PEG-MGF and MGF is that the latter stimulates myoblasts through the stimulation of different receptors. Whereas PEG-MGF increases the muscle stem cell count so that many more cells fuse and become a part of adult muscles.