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MGF is a splice variant of the IGF produced by a frame shift if the IGF gene.

Original price was: R930.Current price is: R837.

SKU: KP044


Mechano Growth Factor, is a new and innovative form of the IGF produced by a frame shift if the IGF gene, namely Mechano Growth Factor, which is PEGylated to improve stability that outperforms natural MGF many times over. MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the bloodstream. Synthetic MGF is water based and when administered intramuscularly, travels into the bloodstream.

MGF is only stable in the blood stream for only a few minutes. Research has shown that PEG-MGF helps increase the muscle stem cell count, so that more may fuse and become part of adult muscle cells.

PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down. Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.

Mechano Growth Factor exhibits local effects in skeletal muscle and without cannot travel through the body without modification.

The problem with synthetic Mechano Growth Factor (MGF) is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Growth Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream. It is also short acting, so stability is not an issue. By PEGylating the Mechano Growth factor (MGF) it is almost as efficient as local produced Mechano Growth Factor when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule.

The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein

Recently peg-mgf has gained a lot of popularity due to its various benefits. Not only does it help in adding new muscle growth, but it also helps cure few muscle disorders. As it helps in strengthening bones too you can also use it for bone-related diseases.

PEG-MGF results are quite fascinating. It produces new muscle fibers and helps to stimulate growth in affected areas. It may also promote the retention of nitrogen in muscle fibers while increasing protein synthesis.

This peptide can be very helpful to bodybuilders as they help in creating new muscle tissues, which in turn would increase the total muscle mass of the body.

Here are a few benefits of PEG-MGF:
• Promotion Of Skeletal Muscle – Research has found that whenMGF is injected directly into the muscle it helps to protect it. In doing so it decreases the expression of some specific inflammatory hormones and lowers the oxidation stress.
• Anti-aging Benefits and Fat Metabolism – This happens when MGF stimulates the IGF-1 receptors which lead to decrease aging and an increase in lean body mass. Along with that, it poses a significant role in fat metabolism.
• Heart Muscle Repair – MGF inhibits apoptosis that cardiac muscle cells go through after hypoxia. MGF helps in the recruitment of the cardiac stem cells to the injured site, and it may help to heal the heart after a heart attack.

Additional information

Chemical Composition

Pegylated Mechano Growth Factor



Pack Size

10 Vials


Keifei Pharma

Dosage Instruction

PEG-MGF dosage of 1mg per day with a typical cycle length of 4-6 weeks. It is injected subcutaneously.


The most preferable way to take PEG-MGF is to inject it intramuscularly. But due to its long half-life, you can also inject it under the skin into the fat tissues (belly, buttocks, thighs). Even if you inject it under the skin, it will still make its way to the receptors present on the muscle cells and be as effective.


Indeed, there are many positive effects associated with PEG MGF peptide based on scientific research and animal testing. But it is important to keep in mind that there have been some records of unfavourable effects related to PEG-MGF.
These negative PEG-MGF side effects are

  • One of the negative effects of PEG-MGF found after animal testing is Hypoglycaemia or ‘low blood sugar’. As PEG-MGF increases the efficiency of cellular functionality, blood sugar achieves its functional goal too quickly thus resulting in Hypoglycaemia.
  • Swelling of the extremities which mean limbs, arms, and legs (particularly hands and feet)
  • The blood pressure of the body drops, in some cases, when you take this peptide.
  • It is also associated with irregular cardiovascular activities. So much so that it can even lead to cardiac arrest in some cases.

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