Dosage Instructions
1.25mg-2.5mg /day
Even at very low doses Letrozole is a potent drug so you do not require a lot of it to benefit from its full effects. Unlike with many of the other AIs or SERMs you might use as a steroid user where doses are normally higher than those used for medical treatment, with Letrozole we can get away with using a similar dose or even lower than is administered when the drug is used medically.
Letrozole Dosage During Anabolic Steroid Use
Making the mistake of taking too much Letrozole during steroid use will have no benefit and bring about negative effects, like fatigue. So, it’s critical to maintain a sensible dose.
With a medical dose usually around 2.5mg daily, we would look at no higher than that and most of the time even lower. To protect from estrogen related side effects during steroid use a dose of as low as 0.5mg to 1.25mg every two days is often enough for excellent estrogenic related protection for most men.
Only if you are experiencing early signs of gynecomastia would increasing the dose at this time up to 2.5mg per day can potentially even fully reverse the symptoms; but be prepared for a noticeable zap in energy during this time. Once gyno symptoms subside it’s important to reduce your Letrozole dose back down to regular estrogenic protection levels.
Female Letrozole Dosage
Increased estrogen levels are not anywhere near as great a concern for female steroid users as it is for males. The main reason for using an AI like Letrozole by females would be to mitigate water retention, especially for competitive bodybuilders or physique athletes where this is most important.
In fact, Letrozole is not recommended as a first choice for females due to its potency in reducing estrogen so much, hence why it is not used medically by females who have not gone through menopause. Females who are determined to use this AI are advised to dose at just 0.5mg every other day and gauge results and effects from there.
Letrozole Dosage for Increased Endogenous Testosterone Secretion and PCT
This AI may have some ability to raise testosterone levels mainly through its ability to reduce estrogen. Both luteinizing hormone and follicle stimulating hormone have shown to be able to be increased by Letrozole and these are essential to the production of testosterone.
So, while a reduction of estrogen is important for bringing about a rise in testosterone levels, this is a fine balance in men and reducing estrogen too low can actually have the opposite effect with testosterone not able to increase to a normal level if estrogen is suppressed too powerfully, which Letrozole has the ability to do.
For this reason, many will choose not to make use of this drug during post cycle therapy at all, in favor of using a SERM like Nolvadex. However, if you find that Letrozole is preferable for you for post cycle therapy use, a low dose similar or lower to that stated above for during your steroid cycle is the only way to reduce the risk of very low estrogen occurring.
Making use of Letrozole alongside Nolvadex, which is a staple in PCT for most men, results in both drugs making the other less effective. Combining these drugs is not recommended for PCT and therefore most people will opt simply to use the better PCT option in the SERM Nolvadex while enjoying the benefits that Letrozole can provide during the steroid cycle only.
Letrozole vs Arimidex for PCT
Letrozole and Arimidex are very similar compounds. Both are nonsteroidal aromatase inhibitors, and both are favored by anabolic steroid users to prevent estrogenic side effects. Both drugs have a similar side effect risk profile.
Out of these two AIs, Arimidex generally takes the lead as being more widely used by bodybuilders, but this can come down to several factors including availability, cost, and wanting to follow in the path of what friends and online acquaintances might recommend.
While both AIs can help stimulate natural testosterone production, neither are considered by most guys to be the right choice for PCT when used alone; in fact, many people won’t use a powerful AI like Arimidex or Letrozole during PCT at all and instead go for a SERM drug with Nolvadex being a popular choice, alongside Clomid and often HCG as well.
The main reason for this is that Arimidex is very good at lowering estrogen, and Letrozole even more so. They are so powerful at this task that they can result in estrogen levels that are too low even for the male body.
This causes complications in the hormonal balance and will have a negative impact in your natural testosterone recovery; males still need a small amount of estrogen to keep things in balance and since PCT is all about getting your natural hormone function back to normal, continuing with a high estrogen suppression drug like Letrozole or Arimidex after the steroid cycle can make this difficult, if not impossible.
Another issue when considering the use of Letrozole during PCT is that when it is combined with the staple PCT drug of choice for most people, Nolvadex, a negative interaction occurs where the concentrations of drugs counteract each other. This is also an issue when Arimidex is combined with Nolvadex.
This is another reason why combining either of these AIs with a SERM during PCT is not advisable at all – and since a SERM is basically essential for PCT it is going to take priority over either Letrozole or Arimidex. Both AIs offer far more advantages when their use is limited to during your steroid cycle where you can greatly benefit from their powerful anti-estrogen effects during that time.
