Description
IGF-1 LR3 is a hormone that functions as the major mediator of growth hormone (GH)-stimulated somatic growth, as well as a mediator of GH-independent anabolic responses in many cells and tissues. Insulin-like Growth Factor-1 is a small peptide (molecular weight 7647) that circulates in serum bound to high affinity binding proteins. It is an unusual peptide in this regard since it is more than 99 percent protein-bound.
It is synthesized by multiple mesenchymal cell types. As a result, there are two major mechanisms of IGF-1 regulation:
●IGF-1 that is synthesized in the liver and secreted into the blood is under the control of GH.
●Autocrine/paracrine IGF-1 is synthesized in peripheral tissues, such as bone. Its synthesis is controlled by GH and by factors that are secreted locally by the surrounding cell types. Some of the secreted autocrine/paracrine IGF-1 enters the systemic circulation. Therefore, understanding the regulation of autocrine/paracrine synthesis of this peptide is necessary to interpret changes in serum IGF-1 concentrations.
Insulin-like Growth Factor-1 exerts its effects via activation of the Insulin-like Growth Factor-1 receptor. This receptor is widely distributed, which enables blood-transported IGF-1 to coordinate balanced growth among multiple tissues and organs. In contrast, autocrine/paracrine Insulin-like Growth Factor-1 can stimulate local, unbalanced growth independently of systemic GH. Examples of this type of growth regulation are wound healing and growth of the contralateral kidney after unilateral nephrectomy.
Dosage Instructions
Injected via Subcutaneous injection after a workout at 20 – 40mcg per day with a typical cycle length of 4-6 weeks
Side Effects
Taking growth hormone can impact how the body responds to insulin which controls blood glucose levels. Untreated growth hormone deficiency can lead to high cholesterol and osteoporosis. Although growth hormone injections are relatively safe and effective, there are a few side effects. Fortunately, serious side effects are rare.
Swelling, numbness, and joint and muscle aches and pains are the most common side effects. You may experience these side effects if you’re getting more growth hormone than you need.
If you have these symptoms, talk to the physician immediately to adjust the amount of growth hormone you are taking.
Some possible side effects with IGF-1/LR3 could be:
- Joint pain
- Muscle pain
- Headaches
- Nausea
- Hypoglycemia
- May be associated with an increased risk of developing a number of common cancers, including lung, breast, colorectal, and prostate
Shipping & Returns
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How do I know that my order has been received?
When your order has been successfully received by our system, you’ll see a confirmation page. A confirmation email will also be sent to the e-mail address you specified, giving the details of your order. This confirmation indicates that your order has been received. If you can’t find this confirmation email, check your spam or junk mail folders.
Fulfilment of your order may be impacted by stock availability however an email will be forwarded to you once your order is packed and ready for shipping. This email will include tracking details so that you can trace your parcel.
I live outside of South Africa, can I place an order?
Unfortunately, we only deliver to addresses within South Africa at this stage.
I live in South Africa, how much does shipping cost?
Shipping from our Anabolics ZA site is only R 150 nationwide!
When will the delivery arrive?
All orders are sent via a door-to-door courier service. Please make sure that there is someone to receive your order at your nominated address between Monday to Friday, 9:00am-5:00pm. Please note that your order will take 2 – 3 working days from the date of payment to arrive. Deliveries to outlying areas may take longer.
Can I make a change or cancel my order after purchasing?
No changes and cancellations are not possible once the order has been processed and an order confirmation screen is displayed.
What is the return policy and process?
Anabolics ZA products are medicines so we cannot refund or accept returns. If you are unsatisfied with your order in any way, please contact us within 30 days of your order via email and we will do our best to resolve your issue.
I have an issue with my order – what do I do next?
Contact us if you have any queries about your order. Refer to your order number as a reference.