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IGF-1 DES, also known as des-acyl ghrelin, is a growth hormone-releasing peptide that is used to increase muscle mass and strength, promote healing and recovery, and improve overall health and wellness.

Chemical Name: Des(1-3) IGF-1

Molecular Weight: 8.1 kDa

Formula: C121H180N40O31

Original price was: R220.Current price is: R198.

SKU: NL078


IGF-1 DES 3 is a modified form of Insulin-like Growth Factor 1 (IGF-1), a protein that plays a critical role in muscle growth and development. IGF-1 DES 3, specifically, is truncated to be more potent and have a shorter half-life, which makes it particularly interesting for bodybuilding and athletic performance enhancement. This form is often used for its ability to stimulate muscle hypertrophy and aid in recovery.

Mechanism of Action

**1. **Increased Protein Synthesis:**

IGF-1 DES 3 binds to IGF-1 receptors on muscle cells, initiating a cascade of anabolic processes that increase protein synthesis. This leads to muscle growth and repair.

**2. **Enhanced Muscle Hyperplasia:**

Unlike regular IGF-1, IGF-1 DES 3 is believed to be more effective in promoting muscle hyperplasia, the formation of new muscle cells. This can contribute to long-term muscle growth beyond the hypertrophy seen with traditional training.

**3. **Localized Effects:**

Due to its shorter half-life, it works effectively when injected directly into specific muscle groups. This localized administration targets growth in particular areas, making it ideal for bodybuilders looking to improve certain muscle groups.

Usage in Bodybuilding

**1. **Dosing and Administration:**

IGF-1 DES 3 is typically used in microgram doses rather than milligrams, reflecting its high potency. A common approach is to inject it directly into the muscle post-workout. This capitalizes on the increased blood flow and nutrient uptake in muscles that have just been trained.

**2. **Cycle Length:**

Users often cycle it for short periods, such as 4-6 weeks, followed by a break. This minimizes the risk of desensitization to the compound and potential side effects.

**3. **Combination with Other Compounds:**

To maximize results, bodybuilders frequently stack IGF-1 DES 3 with other performance-enhancing drugs like anabolic steroids or peptides. The combination can amplify muscle growth, recovery, and overall athletic performance.


**1. **Rapid Muscle Gains:**

Due to its potent anabolic effects, users can experience significant muscle growth and strength gains within a short period.

**2. **Improved Recovery:**

IGF-1 DES 3 helps in faster recovery from intense workouts by repairing muscle fibers more efficiently. This allows athletes to train more frequently and with greater intensity.

**3. **Enhanced Fat Loss:**

Although primarily anabolic, IGF-1 DES 3 can also aid in fat loss by promoting a more favorable metabolic environment for muscle building and fat burning.


IGF-1 DES 3 is a powerful tool in the bodybuilding arsenal, offering significant muscle growth, recovery enhancement, and localized hypertrophy. Its ability to stimulate both muscle hypertrophy and hyperplasia makes it highly desirable for athletes looking to push their physical limits. While the compound is potent and effective, careful attention to dosing, cycling, and combination with other supplements is crucial to maximize benefits and minimize risks. Proper usage can lead to rapid and substantial improvements in muscle mass, strength, and overall body composition.

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