MOTS-c is a small peptide, derived from the mitochondria, that plays a crucial role in regulating various bodily functions, particularly energy metabolism and stress response.
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Origin: It’s a 16 amino acid peptide encoded within the mitochondrial DNA.
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Function: MOTS-c is released into the bloodstream, particularly in response to stress or exercise. Once in circulation, it travels to the nucleus of cells and influences gene expression, impacting how cells utilize energy.
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Key Roles:
- Energy Metabolism: MOTS-c helps regulate glucose metabolism, improves insulin sensitivity, and promotes the breakdown of fats for energy.
- Stress Response: It activates cellular defense mechanisms, protecting cells from oxidative stress and damage.
- Exercise Mimicry: Interestingly, research suggests that MOTS-c can mimic some of the beneficial effects of exercise, even in the absence of physical activity.
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Potential Benefits:
- Improved Metabolic Health: May help prevent or manage conditions like type 2 diabetes and obesity.
- Enhanced Exercise Performance: May improve endurance, strength, and recovery.
- Anti-aging Effects: May contribute to healthy aging by protecting cells from oxidative stress and promoting cellular repair.
