HCG – Human Chorionic Gonadotropin

HCG 5000IU is a hormone commonly used to stimulate natural testosterone production, maintain fertility, and prevent testicular atrophy during or after anabolic steroid use. It mimics the action of luteinizing hormone (LH), which signals the testes to produce testosterone.

HCG 5000IU is sold as 1 lyophilized vial, typically paired with an ampule of bacteriostatic water for reconstitution prior to use.

R300.00

Availability: In stock

SKU: UPA057 Category: Tags: ,

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Description

Human Chorionic Gonadotropin (HCG) is a naturally occurring hormone found in high levels during pregnancy. In men, it is used to replicate the function of LH, thereby stimulating the testes to produce testosterone and maintain normal testicular size and function. This makes HCG 5000IU especially valuable during post-cycle therapy (PCT), bridging between cycles, or as an ongoing protocol in testosterone replacement therapy (TRT) to prevent testicular shutdown.

It is also medically used to treat hypogonadism and male infertility. In bodybuilding, HCG helps retain fertility, maintain endogenous testosterone production, and avoid symptoms of low testosterone during or after suppressive anabolic cycles.

Benefits

  • Stimulates natural testosterone production

  • Prevents or reverses testicular shrinkage

  • Helps maintain fertility during steroid or TRT use

  • Supports libido and mood during PCT or TRT

  • Can improve semen volume and quality

  • Effective bridge compound during off-cycle periods

Side effects
HCG 5000IU is generally well-tolerated, but potential side effects include:

  • Estrogen-related side effects (water retention, mood swings, gynecomastia) due to increased testosterone aromatization

  • Injection site irritation

  • Headaches or fatigue (rare)

  • Desensitization to LH stimulation with excessive long-term use

Using an aromatase inhibitor (AI) such as Arimidex or Nolvadex alongside HCG can help manage estrogen-related effects.

Dosages & Protocol

Dosages for Men:

  • During cycle (testicular support): 250–500IU 2–3 times per week

  • Post-cycle therapy (PCT):

    • 1000IU every other day for 2 weeks

    • Follow with a SERM like Clomid or Nolvadex

  • For fertility support: 1000–2000IU every other day for several weeks (as prescribed)

PLEASE MAKE USE OF OUR PEPTIDE CALCULATOR FOR FURTHER DOSAGE GUIDANCE.

How to administer – reconstitution and injection

Reconstitution:

  • Mix the 5000IU vial with 1–2ml of bacteriostatic water

  • Inject the water slowly into the vial

  • Swirl gently until completely dissolved

Injection:

  • Use an insulin syringe (1ml)

  • Inject subcutaneously into the abdominal fat

  • Dosing reference (if mixed with 1ml):

    • 250IU = 5 units

    • 500IU = 10 units

    • 1000IU = 20 units, and so on

Storage

  • Before reconstitution: Store in a refrigerator or cool, dry place

  • After reconstitution: Refrigerate at 2–8°C and use within 30 days

  • Do not freeze. Protect from direct sunlight

Half life & detectability
Half-Life: Approximately 3–5 days, allowing for 2–3 injections per week
Detection Time: Detectable in advanced doping panels for up to 10 days or longer after the last injection
For athletes subject to drug testing, it is crucial to consider these detection times to avoid positive tests for banned substances.

Additional information

Chemical-composition

HCG 5000 Chorionic Gonadotropin

Strength

5000iu

Pack-size

1 Vial

Laboratory

U.P.A.

Dosage Instructions

Dosage Instructions

2500iu -7500iu’s per week via subcutaneous abdominal injection with a typical cycle length of 4-6 Weeks.

Whichever purpose you are using HCG for – on cycle or for PCT – the dosage and administration of this hormone is very sparse and controlled and unlike that of any other compound you will be using whether that be steroids themselves or drugs like SERMs and AIs.

When buying HCG from your chosen source you will normally receive a small packet of powder containing the active ingredients and another with sterile water in it. These two items are to be mixed to form your injectable ingredient. Any leftover must be refrigerated for later use – do not store the solution at room temperature.

HCG Dosage During Anabolic Steroid Use
When using HCG during your steroid cycle you will want to take it no more than once every 3 to 5 days at a maximum. This will come as some relief since HCG is an injection, so you won’t have to be adding an extra injection to your steroid program too often.

A very low dose of HCG during this time is considered sufficient and this is usually in the realm of 250iu. There is no benefit to increasing the dose beyond this level, nor the frequency of administration.

This modest dosage is enough to give you all the benefits you want from HCG without putting your future testosterone restoration at risk by having the body become dependent on HCG which is an increased risk when you increase the dose – therefore, 250iu once every 5 days is suitable for most male steroid users while on cycle.

HCG Dosage for Increased Endogenous Testosterone Secretion and PCT
HCG is most used as a kick start to your PCT cycle in preparation for the use of SERMs afterwards. The length and dose of HCG during this time should be determined on how powerful your steroid cycle was and the level of testosterone suppression it is likely to have caused.
This can be difficult for new steroid users to gauge initially so a lower HCG dose is advised in those circumstances.

Many users will take HCG for a period of two to three weeks with doses every 3 or 4 days starting at 1000iu at the low end right up to 4000iu. This higher dosage is advised only for advanced users who have used HCG previously and understand its effects. Following this short HCG cycle, SERM administration can begin to carry through the rest of your PCT phase.

Effect on Cycle

Effect on Cycle

HCG & STEROIDS:

For steroid users who make use of HCG while using anabolic steroids the intent is to use this hormone to address the suppression of natural hormones that takes place when you use most types of steroids.

 

During this time your normal testosterone production and levels will be extremely low or even non-existent and the use of HCG during steroid use can prevent the problem of testicular atrophy but more importantly, taking HCG during a steroid cycle helps prime the body for recovery once your cycle ends.

So, what’s the downside to HCG and why doesn’t everyone just use it during a cycle? One of the commonly overlooked issues is the way the male body can become dependent on HCG’s supply of what is basically exogenous luteinizing hormone. Guys who take too much HCG or don’t seriously regulate use of it are at higher risk of dependence.

Those men who go overboard with their use of HCG during a steroid cycle, either through lack of knowledge or a false belief that more equals better, can quickly find themself suffering with a low testosterone condition. Those who know how to use HCG responsibly during a steroid cycle however will reap the benefits and avoid the problem of dependence occurring.

 

HCG VS AROMATASE INHIBITORS VS SERMs

HCG is very different from both SERMs and aromatase inhibitors (AIs).

 

Both SERMs and AIs are medications that have been designed to either block specific estrogen receptors (in the case of SERMs), or to lower overall estrogen levels (AIs). HCG on the other hand is a naturally occurring hormone produced in women once they fall pregnant.

HCG does not target estrogen in any way, but instead is able to directly help stimulate testosterone in men because it works in a very similar way to luteinizing hormone.

Both SERMs and AIs are mainly used to treat breast cancer in women. HCG is used medically to treat low testosterone and infertility and men, as well as fertility problems in women. All three categories of substances are therefore available with a prescription. While both SERMs and AIs are available as different products with slightly differing chemical structures and effects between them, HCG is the only one of the three that is a single hormone with no variation between products.

HCG is available in injection form only, while AI and SERM drugs are oral tablets that need to be taken more regularly than the once or twice weekly injections that HCG is normally administered by.

HCG is not intended to replace either SERMs or AIs at any point during or after a steroid cycle. Instead, it can be a very useful addition but one that needs to be used carefully and with knowledge of both how to dose it properly and what it can and can’t do both in benefits and side effects. Over-use of HCG can have the opposite of your intended effect: instead of improving or restoring your testosterone you could find yourself back in a low testosterone state.

 

HCG FOR POST CYCLE THERAPHY:

Post cycle therapy use of HCG is the most common reason guys will use this hormone for the purpose of optimizing recovery after a steroid cycle. The power of this hormone for PCT use comes with taking it before starting a SERM cycle.

 

Most PCT plans will include either or both SERMs Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate) and while these are generally very effective on their own, many steroid users find that adding HCG to the PCT phase provides enhanced recovery benefits.

 

The strategy here is to make use of HCG prior to starting your regular SERM dosage, with HCG essentially acting as a kick start to the hormone production process thanks to the way it mimics luteinizing hormone. The SERMs then take over for the rest of your PCT cycle, providing a more efficient and effective recovery.

 

This type of PCT plan provides for the two main purposes of post cycle therapy: to help you maintain your gains and to speed up the restart of natural testosterone production; this hormone will be in a greatly suppressed state at the end of your steroid cycle in most cases and without a proper PCT plan the rate of recovery is extremely slow which puts you in the certain position of low testosterone and the associated symptoms and muscle loss.

HCG will usually be started within a 4-to-6-week period after the end of your steroid cycle, but the timing will depend on the steroid compounds you’ve used. Those who are concerned about possible estrogenic side effects from using HCG during PCT, because of increased aromatase activity, might also choose to include an aromatase inhibitor into their PCT plan.

 

This is not always an effective idea because AIs come with their own set of issues when it comes to potentially negatively impacting on testosterone levels because of powerful estrogen suppression; in general, HCG is utilized for a short time frame during PCT, so side effects are not a great concern for most users.

Side Effects

Side Effects

One of the great positive about HCG is that side effects are rare to non-existent. Unlike other substances used by steroid users like SERMs and AIs, HCG is not a drug developed in a lab but instead is a naturally occurring hormone. This means we don’t have to worry about adverse effects like headaches, upset stomach or other common problems that come about with the use of powerful medications.

HCG can raise testosterone levels so the main effects to watch out for relate to rising levels of the hormone and these can come in the form of an estrogenic nature. Water retention and gynecomastia are possible but are considered rare particularly because HCG is not often used on its own but instead combined with anti-estrogen drugs that will themselves mitigate these side effects when you are on a steroid cycle.

Because of the increase in circulating testosterone and DHT, androgenic side effects can be a concern, and this might include increased oily skin and acne, increased body hair growth, and hair loss on the head but the risk of these adverse effects is highly individual and usually only affect men who are genetically predisposed to them, in the same way that androgenic side effects come about from steroid use.

With the use of HCG during post cycle therapy you are likely to be using it at higher doses, this is balanced by the fact that your use of HCG is also likely to be only for a short period of time so the risk of side effects during PCT is again quite low. All of these factors make HCG a hormone that is unlikely to cause you many or any problems at all and possibly is the most side effect friendly substance you will take at any time of anabolic steroid use.

The greatest risk with HCG is not in the form of traditional types of side effects that we see with steroids or other drugs, but rather whether the body starts becoming dependent on the external form of luteinizing hormone that you’re consuming.

When this happens, you will have the reverse effect occur – instead of testosterone levels rising or maintaining at a healthy level with the help of HCG, you’ll be back down to low testosterone because the testicles have become reliant on the amount of HCG you’re taking in. This is avoided with low dosing and only using HCG for a minimal period of time.

Below are some side effects you might experience:

  • Pelvic pain
  • Swelling of the hands or legs
  • Stomach pain and swelling
  • Shortness of breath
  • Weight gain
  • Diarrhea
  • Nausea or vomiting
  • Urinating less than normal

Shipping & Returns

Shipping & Returns

Looking for a bit more information about how online orders are processed? Here are some commonly asked questions and answers regarding our Online Shop!

How do I know that my order has been received?
When your order has been successfully received by our system, you’ll see a confirmation page. A confirmation email will also be sent to the e-mail address you specified, giving the details of your order. This confirmation indicates that your order has been received. If you can’t find this confirmation email, check your spam or junk mail folders.

Fulfilment of your order may be impacted by stock availability however an email will be forwarded to you once your order is packed and ready for shipping. This email will include tracking details so that you can trace your parcel.

I live outside of South Africa, can I place an order?
Unfortunately, we only deliver to addresses within South Africa at this stage.

I live in South Africa, how much does shipping cost?
Shipping from our Anabolics ZA site is only R 150 nationwide!

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All orders are sent via a door-to-door courier service. Please make sure that there is someone to receive your order at your nominated address between Monday to Friday, 9:00am-5:00pm. Please note that your order will take 2 – 3 working days from the date of payment to arrive. Deliveries to outlying areas may take longer.

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Anabolics ZA products are medicines so we cannot refund or accept returns. If you are unsatisfied with your order in any way, please contact us within 30 days of your order via email and we will do our best to resolve your issue.

I have an issue with my order – what do I do next?
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HCG - Human Chorionic Gonadotropin UPAHCG – Human Chorionic Gonadotropin
R300.00

Availability: In stock

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