This medication is used to treat high levels of prolactin hormone in your body. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnant. High levels of prolactin in men can cause symptoms such as enlarged breast and decreased sexual ability/desire. Cabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.
R500
Dostinex, also known as cabergoline, is a medication primarily used to treat hyperprolactinemia, a condition characterized by elevated levels of prolactin hormone in the blood. Prolactin is responsible for stimulating milk production in the breast glands, but high levels can lead to various health issues, including irregular menstrual periods, infertility, and breast milk production in men and non-pregnant women.
Cabergoline works by stimulating dopamine receptors in the brain, which inhibits the production and release of prolactin from the pituitary gland. By reducing prolactin levels, Dostinex helps restore hormonal balance and alleviate symptoms associated with hyperprolactinemia.
In addition to treating hyperprolactinemia, Dostinex may also be used off-label for other conditions, such as Parkinson’s disease and certain types of pituitary tumors called prolactinomas. In Parkinson’s disease, cabergoline helps alleviate symptoms by acting as a dopamine agonist, mimicking the effects of dopamine in the brain and improving motor function.
Dostinex is available in the form of oral tablets, typically taken once or twice weekly, as prescribed by a healthcare professional. The dosage and duration of treatment may vary depending on the individual’s condition and response to therapy. It’s essential to follow the prescribed dosage and instructions provided by a healthcare provider to ensure safe and effective use of Dostinex.
While Dostinex is generally well-tolerated, it may cause side effects in some individuals, including nausea, dizziness, fatigue, constipation, and headache. Rare but more serious side effects such as hallucinations, confusion, and heart valve problems may occur, particularly with long-term use or high doses of the medication. Patients should be monitored regularly by a healthcare provider while taking Dostinex to assess treatment efficacy and detect any potential adverse effects.
Overall, Dostinex is an effective medication for managing hyperprolactinemia and related conditions, helping restore hormonal balance and improve symptoms.
Take this meication by mouth with or without food, usually twice a week or as directed by your doctor.
The dosage is based on your medical condition and response to treatment (prolactin levels). Your doctor will start you at a low dose and slowly increase your dose over several months to help decrease side effects. Follow your doctor’s instructions carefully.
Take this medication regularly to get the most benefit from it. To help you remember, mark the days on the calendar when you need to take the medication.
Tell your doctor if your condition persists or worsens.
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The recommended dosage of DOSTINEX Tablets for initiation of therapy is 0.25 mg twice a week. Dosage may be increased by 0.25 mg twice weekly up to a dosage of 1 mg twice a week according to the patient’s serum prolactin level. Before initiating treatment, cardiovascular evaluation should be performed and echocardiography should be considered to assess for valvular disease.
Dosage increases should not occur more rapidly than every 4 weeks, so that the physician can assess the patient’s response to each dosage level. If the patient does not respond adequately, and no additional benefit is observed with higher doses, the lowest dose that achieved maximal response should be used and other therapeutic approaches considered. Patients receiving long term treatment with DOSTINEX should undergo periodic assessment of their cardiac status and echocardiography should be considered.
After a normal serum prolactin level has been maintained for 6 months, DOSTINEX may be discontinued, with periodic monitoring of the serum prolactin level to determine whether or when treatment with DOSTINEX should be reinstituted. The durability of efficacy beyond 24 months of therapy with DOSTINEX has not been established.
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