Cardarine – GW 501516 HD

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Cardarine – GW 501516

Cardarine is one of the more popular SARM-like substances that is especially appealing to those wanting a serious performance boost, with this compound showing great ability to enhance endurance.

This can open doors to results in multiple areas from fat burning and muscle growth by taking advantage of your ability to push harder, to improved athletic performance.

Cardarine also works extremely well when used to support anabolic steroids, making it an excellent addition to a steroid cycle thanks to the way Cardarine can reduce or even prevent some of most worrying side effects many steroids introduce concerning cardiovascular health.

Original price was: R320.Current price is: R288.

SKU: HD045


Cardarine also goes by the name of Endurobol or by its original chemical research name of GW-501516. All these names refer to the exact same compound which has great benefits when used alone, but also some surprising and welcome benefits when combined with certain steroids.

The reason Cardarine became of interest to athletes is because of its effects on physical performance and its ability to offset cholesterol and blood pressure related changes that occur with the use of many steroids. Whether you’re a steroid user or not though, Cardarine offers multiple benefits, and this is what has made it such a popular compound, despite the fact it’s not always one of the easiest to find and purchase in pure form.

Cardarine is well known for its ability to promote improved endurance and more efficient fat burning, but early studies showed other benefits too like reducing cholesterol and preventing oxidative stress on the blood vessels, reducing inflammation on the kidneys and potentially other anti-inflammatory properties. The cessation of research on Cardarine unfortunately prevented any more specific findings in these areas but early results looked promising.

SARMs are known to be included in some authorized supplements as just one of many ingredients, and this can be a risk with Cardarine as well – but users wanting to get the best from this compound will always want to ensure you’re buying the pure form with the highest potency.

Cardarine is not a hormone and has no impact on hormones and this makes it equally useful for both females and males, with women able to utilize the compound at the exact same dosage as men.

Additional information

Chemical Composition




Pack Size

50 Tabs


HD Labs

Dosage Instructions

Although trials on humans were run for 12 weeks, most athletes using Cardarine will normally stick to an 8-week cycle at a dose of between 10mg and 15mg daily.

The optimal cycle length for you should be evaluated over time, and it’s possible that you might benefit by extending your cycle to 12 weeks, but this is recommended as the maximum, while the maximum dosage should not exceed 20mg for more advanced users.

The common dosage range is from 10mg at the low end up to 20mg per day. It is not recommended that anyone exceed 20mg daily of Cardarine and this is more than enough to provide significant benefits particularly when it comes to endurance.

New users will most likely want to start at the lower, yet still effective dose of 10mg daily. Many users will not wish to exceed 15mg daily and only the most advanced users will progress to 20mg per day.

Make no mistake: 10mg per day of Cardarine will provide an exceptional performance boost. Many users won’t even need to exceed that dose. New users will want to evaluate the effects of 10mg and if all is going well, the dosage can be increased to 15mg during the same cycle.

For those using Cardarine mainly to support the negative effects of some steroids like Trenbolone, a 10mg daily dose of Cardarine is usually sufficient to greatly assist in the management of cholesterol and cardiovascular function.

Both men and women can make use of the same doses of Cardarine because there are no virilization effects that female users will experience, unlike with steroids which bring about very serious masculine traits in females.

Likewise for men, the dose is not going to have any effect on your testosterone function because Cardarine has no impact at all on hormonal function. This makes it possible to select your Cardarine dose purely on the beneficial aspects of the compound, rather than having to balance outside effects as we need to do when using steroids.

Effect on Cycle

Your results with Cardarine are going to be heavily focused on the benefits of enhanced endurance as this is where the compound truly shines.
Cardarine starts working very quickly and you should start noticing significant endurance improvements within just the first few days of a cycle. So, whether you’re a weight lifter or endurance athlete, this boost in stamina is going to allow you to work out or compete for longer and at a higher intensity.

The flow on results from this will be whatever your specific goals are to beat a time record, to lift heavier weights with more sets and reps resulting in faster muscle growth, or just to boost your overall fitness and performance.

This is a very versatile compound that will suit anyone from bodybuilders to physique competitors, and especially anyone undertaking endurance exercise like running and CrossFit where you want to be able to push on as long and hard as possible by staving off fatigue.

Cardarine is also useful for fat burning as it was also developed to help treat obesity. Although this is to be expected when your endurance is boosted and you’re ultimately training much harder and for longer, Cardarine can potentially act to burn fat for energy by changing the metabolism to increase the uptake of glucose in skeletal muscle tissue and to stimulate fatty acid oxidation.

If your diet supports the goal of losing fat, Cardarine can only make it easier and comes with the benefit of reducing catabolism or loss of muscle when losing fat. Cardarine is often referred to as primarily a fat loss compound
Another great benefit of Cardarine is that it does not interfere or have anything to do with hormones, so you don’t get testosterone suppression or require PCT afterwards to recover hormonal function.

The benefits of Cardarine are multiple, but they mostly revolve around this compound’s ability to significantly enhance endurance or stamina. This boosts your performance, in any physical activity, by holding off fatigue for longer so you’re able to work out, train, or perform for a longer duration than you normally could. This brings with it faster results in just about any pursuit whether that be cutting or bulking.

An exceptional benefit that we see with Cardarine and one that might be unexpected, is the way it can work so well with certain anabolic steroids to mitigate their often-serious side effects concerning the cardiovascular system.

Because GW501516 was designed to possibly treat some cardiovascular conditions, it’s not a surprise that we can benefit from this. One such steroid that pairs very well with Cardarine for this purpose is Trenbolone. Tren is a steroid that brings with it some concerning side effects for some people where they can develop flu type symptoms and difficulty breathing.

Users who have combined Tren with Cardarine have noticed how this compound is able to reduce or even eliminate the cardio related issues that occur with Tren, making it easier to do cardio exercises. For some steroid users, Cardarine’s effects in this area are enough to include it as a staple in steroid cycles which use Trenbolone specifically for this reason alone and not necessarily for Cardarine’s more direct performance benefits.

One of the aims of Cardarine development was as a treatment for obesity so it’s not unexpected that it is exceptionally useful for fat loss, even in those who have not yet reached a high level of leanness. Just as importantly, Cardarine will help preserve existing muscle as it encourages the body to make much more efficient use of fat as an energy source.

  • Cardarine may lower LDL cholesterol levels as a result, it might decrease the risk of heart attacks.
  • It may also activate the PPARδ receptor, which could have anti-inflammatory properties that reduce oxidative damage to the blood vessels and tissues.
  • The anti-inflammatory properties of Cardarine may also prevent brain cells from oxidative stress and could help reduce kidney inflammations.
  • It tries to enhance nitric oxide levels in your arteries thereby, increasing vascularity and improving the wound healing process.
  • Due to increased vascularity, it could help in boosting your endurance level which might allow you to prolong your workouts.
  • Cardarine also tries to suppress the glucose metabolism in the liver as it could help in switching the energy source from glucose to fatty acids. Therefore, it may boost the fat-burning ability of your body and inhibits insulin resistance.
  • You could say that Cardarine also has a slight ability to enhance lean muscle mass in most cases, but the results may go ameliorated when it is stacked with SARMs.
  • There is no requirement for Post Cycle Therapy after using Cardarine in most cases. This could be because it may not cause any reduction in your testosterone levels. Cardarine could also be used during PCT after a SARM cycle, to avoid gaining body fat.


If you’ve used steroids in the past then there are certain side effects that you are probably familiar with, and you might be wondering whether Cardarine brings about these same side effects.

The good news is that most side effects that we see with most steroids are not an issue with Cardarine. These are the main areas of consideration:

  • Estrogenic and androgenic: unlike some anabolic steroids, Cardarine does not have any aromatizing activity so there are no estrogen related side effects like gynecomastia, water retention or high blood pressure. Cardarine also has no androgenic properties, so you won’t have to worry about Hair loss or acne, and women have no need to be concerned about developing masculine features.
  • Cardiovascular: Cardarine was originally developed with the intention of treating some cardiovascular related conditions, so it comes as no surprise that negative effects on the cardiovascular system are not to be expected when using this compound.


  • Cancer: early research showed that Cardarine could increase the chances of some cancers developing. However, this testing was done with significantly higher doses than any person would consider taking. So, whether a cancer risk exists from the doses that are used for performance enhancement is still unknown; after all, cancer can take many years to begin forming. This potential issue is therefore one that very much puts Cardarine in the “use at your own risk” category.
  • Testosterone: Cardarine does not impact on your testosterone function, so men don’t need to worry about suppression as you do with steroids. But if you are going to combine Cardarine with one or more anabolic steroids then you will still need to follow normal PCT afterwards.
  • Liver: no liver toxicity is known to be caused by Cardarine. Despite this, doses should remain in the low to moderate range.

As we can see, the side effect profile of Cardarine is minimal. Most people will be able to use this compound without negative effects, and this is what makes it so appealing compared with anabolic steroids which come with extensive side effects.

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